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For example, we assumed less than a fully multiplicative model when considering multiple drugs in the same patient, and variation in our assumptions resulted in similar conclusions.
It could also be used to deliver multiple drugs in response to signals from integrated sensors.
In March, Dr. Wang presented data on three cases of gonorrhea in Hawaii with intermediate resistance to one of the cephalosporin drugs and high resistance to fluoroquinolones, the first cases resistant to multiple drugs in the United States.
Reports of anthelmintic resistance to multiple drugs in individual parasite species, and in multiple parasite species across virtually all livestock hosts, are increasingly common.
BACKGROUND: Solid clinical evidence supports the effectiveness and safety of multiple drugs in treating diabetes, dyslipidemia, and hypertension, and numerous fixed-dose combination products (FDCs) containing such drugs have been developed for patients with more severe forms of these diseases.
Careful engineering can result in liposome-based structures that deliver multiple drugs in precise ratios and at high levels without the toxicities that can occur when delivering the medicines without these structures.
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Bacteria resistant to multiple drugs flourished in areas where antibiotics are freely available and tuberculosis control programs are weak, such as the former Soviet Union, says Laszlo.
Microbes that can resist multiple drugs lurked in about half of the more than 300 samples of raw chicken breasts tested by the consumer organization.
Public availability of clinical trial information varied widely by company, and sometimes within companies for those with multiple drugs approved in 2012 (table 1).
Interestingly, the CQR parental clone Dd2 was derived from an Indochina clone, W2, which exhibits an accelerated resistance to multiple drugs (ARMD) in laboratory experiments [ 64].
MCF7/Mitox cells likewise display resistance to multiple drugs, but in contrast to MCF7/D40 cells do not express P-glycoprotein by immunoblot or RNA blot analysis.
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