Sentence examples for multiple drug targets from inspiring English sources

Rational polypharmacology: systematically identifying and engaging multiple drug targets to promote axon growth.

Unlike magic bullets targeting a single disease-causing molecule, a systems drug design is proposed in this chapter to develop multiple drug targets for multiple-target cocktail therapies.

Finally, based on 28 significant proteins of core network markers in the carcinogenesis of four cancers, a systems drug design mechanism is introduced to select multiple drug targets for multiple-target cocktail therapies.

Next, based on the carcinogenesis relevance value, we investigated the common core and specific network marker of four cancers for multiple drug targets with the aim of suggesting potential and relevant medical therapy for cancer.

Hybrid drugs featuring two or more potentially bioactive pharmacophores have been recognized as advanced and superior chemical entities to simultaneously modulate multiple drug targets of multifactorial diseases, thus overcoming the severe side effects associated with a single drug molecule.

Several key features of the synthesized hybrid structures that assert a profound impact on the inhibitory function have also been discussed alongside computational investigations, inhibitor molecular diversity and selectivity toward multiple drug targets.

Multiple drugs targeting reverse transcriptase and protease make it more difficult for HIV to develop resistance.

In cases where multiple drug-target interactions were found, we used the average of the activities.

However, we included multiple drug-target interactions in the external validation set.

In the first step, we generated a system for multiple drug-target identification based on the application of 3D drug similarity into a large target dataset extracted from the ChEMBL.

In many cases a single drug targets multiple proteins, or conversely multiple drugs target a single protein (Additional file 10).