Sentence examples for multiple dosing with from inspiring English sources
The bFGF and IL-8 plasma levels showed no relevant changes after 14 days of multiple dosing with telatinib.
The geometric means for AUC (0 12) and Cmax calculated were within the range of values observed after multiple dosing with 400 mg per b.i.d.
The PBPK model was also able to recover the steady-state plasma levels after multiple dosing with and without the coadministration of KETO.
A scatter plot was used to assess the relationship between Day 14 indacaterol serum concentration and change in QTcF interval from baseline following multiple dosing with indacaterol 150, 300, and 600 μg.
A recent report by Yokota et al. [ 22] using clinical and laboratory parameters similar to this study showed a similar and marked response in Japanese patients with sJIA to multiple dosing with MRA.
A recent pharmacokinetic study reported that after single or multiple dosing with 100 mg/day eplerenone, approximately 10% of the administered dose was removed by hemodialysis (Ravis et al. 2005).
They suggested the use of multiple doses with an appropriate injection volume would achieve maximum therapeutic effects [62].
Individual Cmax and AUC24 values of abiraterone after multiple doses with and without prednisolone were not largely different.
In this review we include community trials that measure effects after a single dose of deworming drugs ('efficacy' measures in the individual), as well as trials of multiple doses with longer follow-up periods.
The incidence of surgical site infection was estimated to be 2.5% for single-dose prophylaxis and 2.0% for multiple doses, with no statistically significant difference between the 2 prophylactic regimes (risk ratio: 1.24; 95% CI: 0.60 2.60).
Pharmacokinetic data indicated plasma accumulation of tivantinib after multiple doses, with an area under the plasma concentration-time curve among HCC patients approximately two-fold higher than in patients with other solid tumours, but there was high interpatient variability.
