Sentence examples for multiple dosing protocols from inspiring English sources

Wherever possible, computational compartmental kinetic modelling should be used to predict optimal doses or multiple dosing protocols, to facilitate more limited sampling (Rowland and Tozer, 1995).

Relatively high levels of antibodies in the blood can be reached either by administering a higher antibody dose, or by applying a multiple dosing protocol [21], [32].

Results: The use of GnRH antagonist in a multiple dose protocol gave a pregnancy rate of 14.28% which was in the range expected for patient with poor response, but with shorter treatment duration and with fewer ampoules of gonadotropins as compared with the use of a GnRH agonist protocol in a depot formulation.

Within Cetrorelix group patients who received CC had a significant shorter duration of stimulation and needed fewer ampoules as compared with patients in the same group who did not receive CC. Conclusions: A GnRH antagonist multiple dose protocol may be the protocol of choice for the treatment of poor responders.

Two protocols has been designed for assisted reproduction technology (ART) treatment: multiple-dose protocol and a single-dose.

To determine the efficiency of a single-dose and a multiple-dose protocol for GnRH antagonist administration.

To investigate the effectiveness of treatment with transdermal testosterone gel (TTG) before controlled ovarian stimulation (COS) using GnRH antagonist multiple-dose protocol (MDP) in low responders undergoing IVF/intracytoplasmic sperm injection (ICSI).

Design: The study population consisted of 21 poor responders who underwent ICSI and treated with Cetrorelix according to the multiple-dose protocol and who were compared with 21 poor responders treated according to the long protocol and who also underwent ICSI.

Both protocols developed so far, the single dose and multiple dose antagonist protocol, are comparable, utilizing data from the large prospective phase IIIb studies.

This fact made the evaluation of a multiple dose regimen protocol surgically impracticable.

To compare the efficacy of microdose GnRH agonist (GnRH-a) flare-up and multiple dose GnRH antagonist protocols in patients who have a poor response to a long luteal GnRH-a protocol.