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"They don't use it every day and they don't use it in multiple doses.
Like Dr. Sheele, he favors more testing of multiple doses.
But the injections were often administered unsafely, with needles either improperly sterilized or used for multiple doses.
The second study, never completed or published, was meant to review the effect of multiple doses of the bone growth product on soldiers treated at Walter Reed.
In a third trial, using multiple doses, the scientists tested 61 people with hypercholesterolemia.
"You certainly don't want to give yourself multiple doses in a short period of time".
*When an unintentional overdose is given, as in multiple doses of acetaminophen in excess of the amount recommended on the label.
The company also said that the F.D.A. had expressed concern about possible microbial contamination when a vial of Avastin was split into multiple doses.
But no trial has been conducted to see how people respond to ongoing treatment with multiple doses of the drug compared with a placebo until now.
A tropical hibiscus (H. rosa-sinensis) that was growing in a pot might need multiple doses of bloom-boosting high-phosphorus fertilizer.
While most conventional antibiotics are a systematic release of therapeutics that require multiple doses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com