Sentence examples for multiple dose groups from inspiring English sources

Multiple dose groups for characterization of dose response relationships.

Our designs can be extended to multiple dose groups in a straightforward fashion.

Data analysis was done using nonlinear mixed-effect modeling (NONMEM version VI 2.0), which analyzed the PD data from multiple dose groups obtained simultaneously from different experiments.

The gut microbiota was analysed in the multiple dose groups with minimal changes observed in the bacterial groups analysed except for total clostridia which were reduced to below the limit of detection by day 4 of dosing.

Lipid levels measured at 1 h before dosing in the single dose groups and at 1 h before dose 3 in the multiple dose groups served as baseline values.

Adding to this number additional patients to compensate for a reasonably likely dropout rate (20%%), and assuming multiple dose groups (low, medium, high) with a placebo control comparator, results in a phase IIB study with approximately 500 subjects.

The influence of 50 mg/kg multiple dose of genistein group was similar with that of 100 mg/kg multiple dose group.

For the multiple dose group, blood samples were collected at 1 h before dose 4 (day 4) and at 24 h after dose 4 to dose 7 (day 5 to day 8).

No covariate, including total dose which was significantly higher in the multiple dose group (20 mg/kg versus 45 mg/kg, p ≤ 0.0001), influenced outcome in the adjusted model at 12 hours.

The multiple-dose groups saw reductions of 38 to 65 percent over placebo, and reductions were as large for those taking Lipitor as for those who were not.

116 volunteers were randomized into single- or multiple-dose groups for oral administration 30 240 mg of PHFST once or 60 120 mg twice daily.