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Multiple dose, cluster randomized trials with long follow-up periods are the best measure of policy effectiveness since they are likely to detect externalities within schools and potential long term benefits.
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multiple dose activated charcoal.
RIPC: Remote Ischemic Preconditioning, SD: Single Dose, MD: Multiple Dose.
However, the poor aqueous solubility of DCU poses a challenge for in vivo dosing in a multiple dose situation.
Due to ease of administration in a multiple dose situation, oral dosing of the nanosuspension was examined initially.
Multiple dose groups for characterization of dose response relationships.
Both trials reported multiple dose adverse effects.
We found possible dose dependent effects in multiple dose regimens but not in single dose regimens.
An effect on average weight was seen in one cluster-RCT assessing long-term multiple dosing in a low-burden community undertaken in 1995 in India (Awasthi 1995 (Cluster)).
There have also been ten trials (Analysis 4.1) that have assessed the effects of multiple doses of deworming, four of which were cluster-RCTs.
"They don't use it every day and they don't use it in multiple doses.
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