Sentence examples for multiple dose artesunate from inspiring English sources

All multiple dose artesunate studies were undertaken in Asia and regression analyses were limited to patients from this region.

In all studies with multiple dose rectal administration with artesunate (all in Asia), a 200 mg suppository was provided sequentially at intervals over 72 hours, resulting in a mean exposure of 7.9 mg/kg over 12 hours and 14.9 mg/kg over 24 hours.

The results indicate that both artemisinin and artesunate, whether as single or multiple dose regimens, induce a superior parasitological response than parenteral quinine over the 24 hours following initiation of treatment.

The crude PRR at 12 hours with a multiple dose was 52.6% compared to a single dose of rectal artesunate at 64.1%.

multiple dose activated charcoal.

A multiple dose, parallel group study was conducted to assess for a drug-drug interaction between the pyronaridine/artesunate (PA) combination antimalarial and ritonavir.

Mean PRRs at 12 hours with single dose artemisinin and single dose artesunate suppositories were 72.3% and 64.2%, respectively.

At 24 hours, mean PRR was 83.1% for single dose artemether and 96.7% with single dose artesunate (p ≤ 0.0001).

Mean total treatment dose during the initial 24 hours with single dose artemether was 6.72 mg/kg compared with 9.4 mg/kg with single dose artesunate.

At higher dose, artesunate exhibited significant increase (P <.001) in LPO in testis of 45-day treated group (group C).

Mean PRR at 12 hours was 53.5% for single dose rectal artemether compared with 73.5% with single dose artesunate (p ≤ 0.0001).