Sentence examples for multiple disulfide bonds from inspiring English sources
Nanobody possessing multiple disulfide bonds is more stable and it could be stored in RT.
PEMs are often cyclic, very small in size (1 2 kDa) and contain multiple disulfide bonds to stabilize the protein fold.
Both GLuc and scFv proteins contain multiple disulfide bonds, and consequently the production of active and properly folded GLuc scFv fusions is challenging.
Engineering a reactive cysteine residue into proteins with multiple disulfide bonds is often a challenging task as it may interfere with structural and functional properties of the protein.
Expression of these molecules in soluble form has met limited success, presumably due to their large size, heterodimeric structure and the presence of multiple disulfide bonds.
A knottin is an extremely stable 30-amino-acid protein fold (<4 kDa) composed of three anti-parallel β-strands connected by loops of variable length and multiple disulfide bonds (Fig. 1F).
Therefore we conclude that multiple disulfide bond cleavages were either not efficient or were not proceeded by efficient backbone cleavages.
α-Lactalbumin was chosen to demonstrate the usefulness of EC/MS for studying proteins containing multiple internal disulfide bonds.
The αβ subunits, colored orange/blue or white in Author response image 1, are linked into αβ homodimers by multiple reciprocal disulfide bonds between α chain cysteines.
The proven therapeutic potential of Tf its large size and the presence of multiple (18) disulfide bonds spread across the protein sequence make it an epitome of modern protein drugs.
However, the refolding of inclusion bodies in vitro is a difficult and complex task, particularly for proteins that have multiple domains and complex disulfide bonds.
