Sentence examples for multiple distinct sites from inspiring English sources
Thus, these data underscore the importance of the CD44 cytoplasmic domain in the function of the extracellular portion of CD44H, and demonstrate a role for ligation of human CD44 isoforms at multiple distinct sites in regulation of expression of CD44 binding to HA.
If MCMs are initially loaded at ORC sites, but for unknown reasons finally reside at multiple distinct sites throughout the 100-kb region, then one MCM hexamer would reside on somatic chromatin each ∼20-kb.
Protein phosphorylation can occur on multiple distinct sites throughput the given protein [ 33, 34].
As with the sialylated protein in the absence of lactose, multiple distinct sites of water occupancy are observed here.
The inteins are inserted at multiple distinct sites, each of which corresponds to a highly conserved region of RNA polymerase.
This method yields a metric that quantifies the influence on overall ligand affinity of ligand binding to multiple, distinct sites within a protein binding region.
The MED-1 sequence is a downstream protein-binding element previously linked to TATA-less promoters with multiple distinct start sites (Butler and Kadonaga 2002).
The differences between the VS and the IS are extended here: whereas secretory lysosomes are secreted into a single synaptic pocket in the cytotoxic synapse [21], [22] (Figure 6A), the tomographic data of the HTLV-1 VS (Figure 4C, Figure 6B) demonstrated multiple, spatially distinct sites of virus budding into synaptic pockets that are separated by areas of close membrane membrane apposition.
Through whole-exome sequencing and chromosome aberration analysis of multiple spatially distinct sites within primary tumors and metastatic lesions, the authors elegantly demonstrated intratumor genetic heterogeneity and constructed phylogenetic trees.
One explanation might be that there are really multiple distinct divalent sensitive sites, and only when the higher-affinity site is weakened, does the second site become revealed.
If these mirs are co-expressed, they may target different mRNAs or might interact with the same target transcripts via multiple, distinct miRNA binding sites.
