Multiple distinct miRNAs from a single precursor were previously described in plants [ 46, 47].
Alternative splicing is an important biological mechanism for producing multiple distinct transcripts from a single gene locus.
A tandem process can be broadly thought of as one in which the substrate undergoes multiple distinct reactions in a single synthetic operation.
This result was obtained regardless of the tissue of origin: both hair and blood yielded multiple distinct sequences, with no single type predominating.
Several studies have, however illustrated significant genetic differences among samples collected from multiple distinct sites within a single river (Elo et al. 1994; Garant et al. 2000, Landry and Bernatchez 2001; Spidle 2001; Primmer et al. 2006).
Based primarily on the findings in humans and/or mice; organisms in which exon skipping is the principal form of alternative splicing, the canonical role of alternative splicing is to facilitate the synthesis of multiple, distinct, transcripts from a single gene.
Consequently, these arguments support viewing the giraffe as containing multiple distinct species rather than a single polytypic form.
Alternative splicing (AS) is a common phenomenon in higher eukaryotes that involves the production of multiple distinct mRNA molecules from a single gene.
A multiplex molecular imaging method, capable of imaging multiple distinct molecular signatures within a single image, is necessary for sensitive detection of molecular and cellular content of heterogeneous tissue that is typical in cancer.
