Sentence examples for multiple distinct binding from inspiring English sources

Owing to the interdependencies between multiple distinct binding events, the behaviour of the components in isolation does not reflect the behaviour of these complexes as a whole.

This homotetrameric protein wraps ssDNA in multiple distinct binding modes that may be used selectively in different DNA processes, and whose detailed wrapping topologies remain speculative.

This may be true for a protein with many permanent interaction partners, because the protein tends to form a permanent complex with its partners through multiple distinct binding interfaces and may have a greater proportion of interface residues [ 22].

The outcome of the reuse of the binding pocket by multiple distinct binding partners and the required complementarity between binding peptide and the binding pocket results in the repeated patterns that we refer to as motifs.

However, a protein with many transient interaction partners may transiently interact with its different partners through the same binding interface (though it is possible that the protein may form a transient complex with its partners through multiple distinct binding interfaces), thus the PPID of the protein may not well reflect the proportion of its interface residues [ 22].

Previously, we reported on multiple distinct phospholipid binding modes of αS with slow binding kinetics.

If these mirs are co-expressed, they may target different mRNAs or might interact with the same target transcripts via multiple, distinct miRNA binding sites.

A multitude of mGlu5 PAMs have been reported across literally dozens of chemotypes targeting multiple, distinct allosteric binding sites with robust in vivo efficacy and safety margins.

For example, in photosynthetic stramenopiles such as Aureococcus anophagefferens there are giant proteins in which the OST-HTH domain occurs with multiple distinct RNA-binding and ubiquitin E3 ligase domains in the same polypeptide and could function as large scaffolds for assembly of RNP complexes (Fig. 2).

Multiple distinct motif-mediated binding and/or modification events can affect each other either positively or negatively to various degrees, i.e. they can induce, promote, inhibit or completely abrogate each other.

This method yields a metric that quantifies the influence on overall ligand affinity of ligand binding to multiple, distinct sites within a protein binding region.