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However, what is surprising is that many signaling pathways are bowtie-shaped (Figure 1): multiple different stresses converge on a single TF, which nonetheless induces multiple distinct and specific gene expression outputs.
Multiple distinct and geographically diverse genotypes of highly pathogenic avian influenza (HPAI) A H5N1 viruses now exist and continue to cause outbreaks of disease in domestic poultry on three continents [1], [2].
Pleiotropy is a feature of some genes, which refers to the ability to affect multiple, distinct and unrelated phenotypes and has important implications in development, disease and evolution [ 1– 4].
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Features of the plugin include: an easy to use interface, design customization, multiple templates for displaying publication results, a caching mechanism to reduce page load times, supports multiple distinct queries and retrieval modes, and the ability to aggregate multiple queries into unified lists.
Our model allows for multiple, distinct goods and market dynamics with buyers and sellers that arrive over time.
However, the insular cortex is functionally heterogeneous, consisting of multiple distinct subdivisions and the FCs between these subdivisions and other pain processing regions remain largely unknown.
The copies of the 'core' genes, e.g. cheAWY, are clustered in multiple distinct locations and additional genes are present (cheC, cheD, cheV and cheX) that generate greater mechanistic diversity [ 5].
Millions of people from multiple distinct ethnic and religious communities in Rojava are having to learn, teach and live a new way of life.
The authors indicate that their pol data contained multiple distinct splits, and that these splits can be explained by different modular, reticulate, and saltational evolutionary events (p. 11).
A set of eighteen earthquake records sorted into three categories of earthquakes were considered, namely: earthquake excitations having (i) a single dominant pulse (ii) multiple distinct pulses, and; (iii) no distinct pulses in their velocity record.
Our simulations show that the proposed estimators have robust performance for sinusoidal signals with multiple distinct frequencies, and they can be used to separate two very close frequencies of an input signal in a highly noisy sampling environment.
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