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When multiple disorders are present, the ophthalmologist attempts to identify the disorder causing the greatest limitation of vision.
Similar changes were also observed in other mental disorders, including Alzheimer's disease, ApoE Ɛ4 allele carriers, traumatic brain injury, major depression, epilepsy and autism [ 12, 31– 36], suggesting that multiple disorders are linked to some analogous disruption of the DMN.
The most frequently offered explanation for the biased estimates from clinic-based samples suggests that individuals with multiple disorders are more likely to be referred for treatment than individuals with a single disorder (Galbaud Du Fort et al. 1993; Kushner et al. 2008).
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Of the remaining 60% of the patients (143/240), multiple disorders were found in 40% (59/143).
Identifying the associations between human protein complexes and multiple disorders is essential for understanding disease mechanism and is also important to assist drug developers for the development of new diagnostics and therapeutics.
Therefore involvement of several different health care providers in managing multiple disorders is inevitable and often results in competing treatments, sub-optimal coordination and communication between care providers, or unnecessary replication of diagnostic tests or treatments [ 3, 7, 8].
Given high rates of comorbidity among mental disorders, better methods to rapidly screen across multiple mental disorders are needed.
The two most studied components of the serotonergic system that have come into the spotlight in determining susceptibility to migraine as well as multiple neuropsychiatric disorders are the serotonin transporter (SERT, also known as SLC6A4), which reuptakes serotonin from the synapse, and monoamine oxidase A (MAOA), an important enzyme that degrades serotonin and metabolizes triptans [23].
Multiple additional neuromuscular disorders are associated with dysphagia.
Multiple human hereditary disorders are linked to mutations in helicase genes.
The Alzheimer's disease (AD) is a neurodegenerative disease that has multiple cognitive disorders, being especially relevant the language impairment displayed by patients diagnosed with the disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com