It has become appreciated that breast cancer is not one disease, but in fact represents multiple disease types, each of which may require a unique treatment.
Mutations at distinct sites in the same mtT-DNA gene sometimes lead to multiple disease types, possibly due to diverse effects on tRNA synthesis, maturation, accepting activity, or stability.
Together, these technologies will help us dissect both the spatial and temporal dynamics of ECM homeostasis, and promote our understanding of the underlying mechanisms that influence cell-ECM interactions in the context of multiple disease types.
Although most previous studies are limited by both the resolution of the genetic map and sample size, there are obvious lessons to be learned from statistical signals detected by multiple GWA studies while limiting disease types by infections tumors or immune disorders.
They may particularly apply in a primary care setting in which different types of PCPs work with the same CDSS covering multiple disease areas of care and multiple types of alerts.
Multiple types of barriers may hinder the use of large-scale implemented CDSSs covering multiple disease areas in primary care.
Using the intensive but clinically relevant approach of chronic systemic delivery, IGF-1 suppressed the autoimmune response in multiple mouse models of autoimmune disease (type 1 diabetes and multiple sclerosis).
There has been, roughly since World War II, an apparent decrease in the prevalence of "traditional" infectious diseases, such as tuberculosis, mumps, or measles, with a concomitant increase in immune-related disorders, such as multiple sclerosis, irritable bowel disease, type 1 diabetes and various allergic diseases.
On the basis of prior evaluations, they show potential to treat multiple diseases, including certain cancers, Type 2 diabetes, and cardiovascular conditions.
Diabetes may elicit an increased compaction rate as well as an earlier onset of cataract formation, though there may be multiple mechanisms of action dependent on disease type, duration, or treatment strategy.
In the past couple of years, with the emergence of genome-wide association studies (GWAS), there has been an explosion of genetic discoveries for many complex genetic autoimmune diseases such as Crohn's disease, type 1 diabetes, multiple sclerosis and rheumatoid arthritis (RA).
