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Such hotspots for multiple disease resistances have been noted in other species, including maize [ 37], rice [ 31], and potato [ 38].
Since virtually all tomato disease resistance genes originate from wild relatives, further knowledge of these genomes will facilitate introgression of multiple disease resistances into elite cultivars.
The two stand-out hotspot regions identified for multiple disease resistances on SBI-10 and SBI-06 contained NBS-LRR gene clusters.
T. dicoccoides deserves to be considered as a potential genetic resource for cereal improvement because wild emmer harbors rich genetic diversity for multiple disease resistances, agronomic traits of economic significance, and environmental adaptations [ 27].
Additionally, hot-spots in the genome for multiple disease resistances are present in sorghum, particularly the short arm of SBI-10 and the long arm of SBI-06, containing 51 QTL for 12 traits from 10 additional studies, as well as the current study [ 3, 7, 47- 54].
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The parents exhibit significant agronomic differences, including adaptation and yield-related traits, end-use quality traits, and multiple disease resistance [ 31, 32]; for example, Ning7840 is resistant to rusts and Fusarium head blight but susceptible to Hessian fly [ 33], whereas Clark has opposite reactions to these pests.
Using multiple disease resistance as target traits, we have identified accessions with potentially new resistance genes in the 3K genomes.
In the mid - 1980s IR64 was released as a variety with broad adaptability, multiple disease resistance and good eating quality.
So far, enhanced resistance against multiple diseases in rice has been reported mostly in lesion mimic mutants (Mizobuchi et al. 2002; Wu et al. 2008), thus, determining how a mutation with no pronounced cell death (lesion mimics) can mediate multiple disease resistance is of practical interest.
Several researchers successfully pyramided QTLs/genes for multiple disease resistance to provide a broader spectrum of resistance than those conferred by a single QTL/gene (Castro et al. 2003; Zhang et al. 2006; Pinta et al. 2013; Sreewongchai et al. 2010).
Consequently, breeding cultivars with multiple disease resistance would help sustain rice productivity.
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multiple disease outcomes
multiple disease pathogeneses
multiple disease factors
multiple disease models
multiple disease targets
multiple disease indications
multiple metal resistances
multiple disease indicators
multiple disease risks
multiple disease states
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multiple disease entities
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multiple drug resistances
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