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These can become involved in multiple disease processes, including mycobacterial infections (Fig. 14) [42], gastric, biliary and hepatic malignancy [43], pancreatitis [44], lymphoma [45], sclerosing mesenteritis [46] and sclerosing cholangitis [47].
So, it is important to have comprehensive search for all the major causes of dyspnea in every patient as significant number of them could be having multiple disease processes responsible for their symptoms.
Therefore, it appears consistent through multiple disease processes that disturbances in the IL-2 and CD25 signaling axis are often paralleled by defective immunoregulation by Treg.
In our study, we directly measured the tissue specific expression of S100B in addition to serum S100B, which represents a collective source from multiple disease processes.
A similar approach, using microarrays, will likely be useful in detecting genes related to multiple disease processes.
IMD has been shown to have pathophysiological effect in multiple disease processes involving the circulatory and renal systems [ 12] and congestive heart failure [ 13].
Similar(47)
However, CAD is the terminal manifestation of multiple intermediate disease processes, which individually have genetic and environmental determinants.
Clinical issue Accumulation of the neuronal protein α-synuclein (aSyn) is associated with multiple neurodegenerative disease processes, including Parkinson's disease.
The effect at this site matched the direction of that reported for asthma, suggesting that this region may harbour mechanisms capable of moderating multiple atopic disease processes.
Population studies of polymorphisms in genes encoding TLRs or their downstream signalling molecules in conjunction with limited extrapolation from animal studies have directly linked these pathways to multiple human disease processes.
However, TRALI is thought to be under-diagnosed and under-reported, particularly in the busy critical care setting where the development of symptoms may be attributed to multiple other disease processes or therapeutic interventions (for example, post cardiopulmonary bypass) rather than transfusion [ 20- 22].
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