Sentence examples for multiple disease pathways from inspiring English sources

Enhancing effector function, antibody drug conjugates (ADC) or targeting multiple disease pathways via multi-specific antibodies are being explored.

The patients with a SALS diagnosis without a SOD1 gene mutation appeared as a more heterogeneous group possibly because of multiple disease pathways.

However, treatment of complex diseases usually requires synergistic delivery of multiple compounds to shut down multiple disease pathways.

Since the existing PAH therapies act by different, yet potentially complementary mechanisms, using combination pharmacotherapy may provide additive and/or synergistic effects by simultaneously addressing multiple disease pathways.

Various pathophysiologic mechanisms and multiple disease pathways have been studied in AF; however common molecular mechanisms underlying the initial development of AF and transition from paroxysmal to persistent AF remain unclear.

Progress in these areas could lead to the identification of novel therapeutic targets and guide strategies for modulating multiple disease pathways, both immune and non-immune, in future clinical trials.

This highlights the need to consider environment, genotype and DNA-M together when seeking to understand the pathogenesis of complex disease, as DNA-M plays a role of integrator of multiple disease pathway signals.

Given the complexity of the APP system, multiple neuronal systems have the potential to regulate the expression and proteolysis of APP and could also initiate imbalance within this system, leading to multiple possible disease pathways.

Human disease should be conceived as resulting from integrated extrinsic and intrinsic causes, with research focused on modern human-specific models to understand disease pathways at multiple biological levels that are analogous to adverse outcome pathways in toxicology.

Multiple biomarkers represent various elements of disease pathways.

Network studies highlight the idea that multiple processes are involved in AD disease pathways, reveal new targets for further investigation and have generated new hypotheses.