Sentence examples for multiple disease mechanisms from inspiring English sources

According to the data, each gene participated in ∼2 chronic disorders on average and thus our findings support the prior isolated observations that genes active in the mechanism of a single disorder may be a part of multiple disease mechanisms [16] [20].

A fundamental problem with this classification system is that the same phenotype may result from multiple disease mechanisms.

Stroke is a heterogeneous syndrome caused by multiple disease mechanisms, resulting in a disruption of cerebral blood flow with subsequent tissue damage.

Our study demonstrated the efficacy of a novel AD therapeutic strategy targeting at multiple disease-causing mechanisms through the synergistic effects of microdose lithium and pyrroloquinoline quinone.

The herbal medicines with multiple components offer a unique opportunity to explore multiple disease-causing mechanisms simultaneously.

Multiple gene clusters, each of which identified a distinct group of subjects, imply multiple causal pies (disease mechanisms) for young-onset hypertension and may help to identify disease sub-types.

Various pathophysiologic mechanisms and multiple disease pathways have been studied in AF; however common molecular mechanisms underlying the initial development of AF and transition from paroxysmal to persistent AF remain unclear.

Spectral-domain OCT permits measurement of the GCL + IPL and other nucleus-containing retinal layers and has increased our understanding of disease mechanisms in multiple sclerosis (Ishikawa et al., 2005; Tan et al., 2008, 2009; Walter et al., 2012).

Such findings further suggest that the loss of normal functions or the gain of abnormal effects by reactive astrocytes may contribute to disease mechanisms in multiple sclerosis and other autoimmune inflammatory conditions.

The unexpected magnitude of this overlap presents the unique opportunity to dissect the pathogenic mechanisms underlying multiple disease states in the expectation that this may lead to both more sensitive diagnostics and novel therapies.

Thus, efficacy resulted from interfering with the activity of multiple cells, and perhaps reducing compensatory disease mechanisms.