One systematic review of intervention models involving CHWs recommended integrated multiple disease case management in sub-Saharan Africa.
On Mayo Clinic Jacksonville Alzheimer's disease cases, multiple linear regression analyses are reported between clinical course (age of onset, disease duration, final MMSE score) and pathology variables adjusted for age at death, brain weight, APOE-ε4, and presence of co-existing Lewy body disease.
Mukherjee et al. [ 19] considered cases having multiple disease states with a natural ordering in matched case-control studies by using conditional adjacent-category logistic regression (ACLR) models in an analysis of low birth weight in newborns.
The specificity of GPC3 as disease biomarkers should be carefully examined and validated in large cohorts, in a comparison among multiple diseases, and in cases of different stages, duration, and severity.
We then extended these models by considering cases that had multiple disease states.
If there are multiple disease loci spread across subsets of cases, we would have had little power to detect them.
28 Power constraints did not allow us to look for multiple disease specific associations, but, in any case, assessing what is a beneficial diet overall rather than a diet focusing on a specific disease (or group of diseases) is an obvious priority.
The BLS nature codes are categorized into Divisions: traumatic injuries and disorders; diseases; multiple diseases and disorders; and cases where there is insufficient information to select any nature code [ 25].
The questionnaire design would then undergo build-in algorithms to filter and consolidate redundant questions (when multiple diseases were suspected in the case) (Figure 1B Steps B1 and B2); the questions were then re-ordered into the final format of the questionnaire (Figure 1B Step C).
Case-management programs for patients with multiple diseases are currently being developed, although mostly in English speaking countries [ 34].
