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Recent reports suggest that US28 might play a causative role in multiple diseases associated with HCMV infection.
For example, multiple CMT disease associated genes affect proteins that regulate endocytic membrane transport and thereby impact neurons and Schwann cells in the maintenance of axon viability.
Over the following years, multiple disease genes associated with cystic kidneys were identified, and almost all of the corresponding gene products were found to localize to primary cilia [1,6].
Multiple disease mutations associated with IPF P33S, L55Q, Pro112ProfsX16, and V144M cluster in TEN-domain of hTERT.
For example even though nanobacteria have been found in multiple disease states associated with calcium deposition, we have yet to fulfill Koch's postulates regarding VOC.
In contrast, modeling the impact of multiple disease variants associated with immune and inflammatory mediators of allergic asthma (group 1 variants) provides a pseudo-continuous log-normal relative disease risk distribution in the population.
Motor function is impaired in multiple neurological diseases associated with corticospinal tract degeneration.
We hypothesize that this type of immunomodulatory approach may produce interference or disruption of β-sheet structures in multiple neurodegenerative diseases associated with pathologic protein conformers.
Consideration of HRQOL is also influenced by women's increased risk of multiple chronic diseases associated with menopause, including osteopenia, osteoporosis and related fractures, and cardiovascular disease [ 16].
The poor social relationships, low socioeconomic status, and the multiple chronic diseases associated with obesity may have predisposed obese people to impaired mental health.
Type 2 Diabetes Mellitus (DM) is a common chronic disease associated with multiple clinical complications.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com