Exact(1)
These biochemical changes in hATSCs induced the functional development of multiple differentiation potencies such as β-cells and neural cells; specifically, the ability to differentiation into GABA-secreting cells was significantly improved in in vitro- and in vivo-induced animal lesions with significantly improved therapeutic modality.
Similar(59)
Furthermore, we conservatively filtered the predictions for expression in multiple cell lines in multiple differentiation stages.
Exogenous Oct4 improves adult ATSCs cell proliferation and differentiation potencies through epigenetic reprogramming of stemness genes such as Oct4, Nanog, Sox2, and Rex1.
The results showed that these hSKPs had multiple differentiation potentials.
The osteogenic- and adipogenic-induced differentiation experiments confirmed that the obtained ADSCs possessed multiple differentiation abilities.
Kwon, A. et al. Tissue-specific differentiation potency of mesenchymal stromal cells from perinatal tissues.
The gene datasets were filtered by SERPINB2 expression profiles and the differentiation potency of stem cells or toxicity-related diseases.
Teschendorff, A. E. & Enver, T. Single-cell entropy for accurate estimation of differentiation potency from a cell's transcriptome.
The results revealed a strong relationship between significantly increased SERPINB2 expression and toxicity-related inflammatory disease (Fig. 3d) or deceased differentiation potency (Fig. 3e).
Resulting stem cell sheets retained their phenotypical profile and mesodermal differentiation potency.
Moreover, ascorbic acid can also stimulate MSC proliferation without reciprocal loss of phenotype and differentiation potency.
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