Sentence examples for multiple differentiation pathways from inspiring English sources

Because NSCs are multipotent stem cells that can follow multiple differentiation pathways, using this differentiated cellular system may allow resident cell replacement and create an environment that supports and improves axon regeneration.

In addition, multiple differentiation pathways can result in production of similar cells such as T and B lymphocytes [16] [18].

Similarly, the genome-wide RNA-seq data from different RMP developmental stages is a valuable resource to further analyse Plasmodium gene function and the regulatory networks underlying the multiple differentiation pathways of Plasmodium.

Deregulation of gene expression by Sp1 deficiency affected multiple differentiation pathways and gene sets, some of which were common between cell types (Cluster 1, 2), but others were unique for each cell type, as demonstrated by clustering of their GO-terms according to P values (Fig. 4B and supplementary material Table S5).

Concomitantly, activation of the AHR/TCDD axis disrupted the concerted expression of genes that regulate multiple differentiation pathways, including WNT and BMP; genes coding for developmental processes such as gametogenesis, cardiac and neural differentiation, extracellular matrix formation, and cell adhesion and migration; and genes encoding chromatin remodeling factors.

We propose a model whereby the Myc/Miz-1 pathway acts as a master switch that represses multiple differentiation related genes.

In some cases, like with differentiating stem cells, multiple control groups would be needed in order to achieve a comprehensive understanding of the differentiation pathways.

Dotted arrows indicate secondary or minor differentiation pathways.

Smoking had no effect on SAE gene splicing, but was associated with a shift in molecular pattern from Clara cell-associated towards the mucus-secreting cell differentiation pathway with multiple features of cancer-associated molecular phenotype.

Here, the operation of such a network is addressed through a focus on murine T cell development, where we have recently established regulatory linkages between GATA-3 and PU.1 and multiple other factors essential to this differentiation pathway.

In vitro experiments have shown that both adipocytes and osteoblasts originate from common progenitor cells, mesenchymal stem cells (MSCs), which are capable of multiple pathways of differentiation, including differentiation into osteoblasts, chondrocytes, myoblasts, adipocytes, and fibroblasts [ 5, 6].