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Multiple different treatments were often given.
Malignant brain tumours are usually treated with a multiple different treatments and typically involve surgery, radiotherapy, and chemotherapy.
Network meta-analyses would benefit from our collected evidence to estimate precise treatment effects for these multiple different treatments.
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"Any time you have multiple different treatment strategies, it tells you that any kind of scientific evidence is really lacking," said Dr. Gordon O. Matheson, a professor who is chief of the sports medicine division at the Stanford School of Medicine.
Most papers provided some information, but it was difficult to assess what constituted good reporting because of multiple treatments, different treatment time points relative to surgery, our lack of specialist knowledge of different cancers and the level of detail reported.
"After multiple bouts of different treatments were found to be ineffective, Pretorius was left with no option other than to retire to ensure he can continue to live as normal a life as possible".
Two-factor RMANOVA followed by the Dunnett post hoc test was used for multiple comparisons between different treatments.
Patients could have had multiple different types of treatment over the 6 year follow-up so patients were classed according to the invasiveness of the treatment as follows: if a patient had CABG any time over the course of the study, they were in the CABG group, if the patient had only had PCI but not CABG, they were in the PCI group, and if the patient had neither, they were in the MM group.
Different letters on bars indicate differences among different treatments at p < 0.05 according to multiple comparison Tukey post hoc range test after GLM.
This test was selected because it allows multiple comparisons among the different treatments (five siRNAs and three treatments including LPS, poly (I C), and non-treatment controls) without dividing the whole data set, which results in a more robust analysis.
Differences among different treatments were analysed at p < 0.05 via multiple comparison Tukey post hoc range test after GLM.
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