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The potential exists for individual subjects to be recruited for multiple different studies at various times and thus share a disproportionate burden for research participation.
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Up-regulated genes in multiple different species/array studies were selected for analysis.
Varying detection rates of multiple viruses in different studies may reflect the differences in the study period and location, study population, environmental factors, the number of respiratory pathogens tested, and/or the diagnostic methods/techniques used.
Statistical analysis of the differences in JMJD2B expression between ER-positive and ER-negative breast cancers was performed using ONCOMINE algorithms that allow for multiple comparisons among different studies.
One example might be a researcher looking to compare certain clinical data such as creatinine levels over multiple treatments in different studies.
The usefulness of new measures is therefore demonstrated by multiple applications in different studies (accumulative body of evidence to support scale measurement properties).
Statistical analysis of the differences in MYBBP1A expression between these tissues used Oncomine algorithms, which provided multiple comparisons among different studies [ 20- 22].
Johnson et al. (2003) provided no rationale for designing their study with a concurrent control five times larger than the treatment groups, which leads us to ask whether the control group reported here is, in fact, a composite of controls from multiple, perhaps five, different studies.
Hegde et al (2013) recently evaluated VEGF levels across different studies (multiple tumour types, multiple comparators and combinations) that included bevacizumab in the treatment arm and found high levels of VEGF to be a negative prognostic factor in line with our findings.
Meta-analysis is an increasingly popular tool for combining multiple different genome-wide association studies (GWASs) in a single aggregate analysis in order to identify associations with very small effect sizes.
The majority of ontology concepts were associated with multiple signatures derived from different studies and organisms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com