This is achieved by supporting early stopping based on the accuracy on a validation set [21] and by providing generalized methods for building multiple networks using different initial weights [22].
Multiple simulations with different initial conditions are performed with customized MATLAB codes.
Confirmation of the optimal smoothing values was obtained via multiple optimizations with different initial conditions (by setting num_restarts = num_time_guesses = 3).
We performed the MULTIDIVTIME analysis multiple times from different initial conditions to confirm convergence of the Markov chain on highly similar resulting time estimates and posterior intervals.
Furthermore, we have found that the optimized CRs are sensitive to the choice of the initial random CRs, and performances can be improved by resorting to multiple runs with different initial conditions.
Conversely, the samplers including 1PB, c2PB, and REV that reach a stationary distribution faster would have potential benefits from exploring optimal networks over the large network space by employing shorter multiple chains from different initial networks.
ICA was performed in multiple runs using different initial values and different bootstrapped data sets by using the ICASSO package (Himberg et al., 2004) with the FastICA algorithm (Hyvärinen and Oja, 1997), which could significantly improve the reliability of the results (Meinecke et al., 2002).
Since fitting nonlinear curves may converge to local minima in the landscape of possible solutions, we tested the robustness of our fits by running our curve fitting programs multiple times with different initial values for the three-parameters β1, β2, and β3.
We perform multiple runs with the same rank parameters and different initial random initializations and construct a set of 20 different connectivity matrices: { C (1 ), …, C (20 ) }.
More recently, Dr Smith and his team have been using clusters of computers around Britain to run multiple models with slightly different initial conditions.
