However, the drawback of all the encodings presented above is that they are either not based on biological processes, or lack the multiple interactions among different developmental phenomena that result in the emergence of biologically plausible models.
Alternately, VHL may be a complex disease that can involve multiple mutations targeting different developmental lineages.
We suggest that the marginally non-significant sex effect in our model could be due to the presence of multiple cohorts with different developmental stages.
In many cases, multiple eyecups at different developmental stages were present within the same well of a differentiating six-well plate.
This microarray has been used to survey the silkworm gene expression patterns in multiple tissues, at different developmental stages, and under various conditions or treatments [ 11– 15].
In SilkDB, 37 ABC genes have evidences of mRNA expression with EST sequences, which were collected from 36 cDNA libraries of multiple tissues during different developmental stages.
In contrast, inflorescence or spike-type cut flowers, which have multiple flowers at different developmental stages, may provide an excellent model for studies of remobilization from senescing to developing flowers.
Leaf, stipule, stem, tendril tissues from multiple nodes (at different developmental stages) as well as the root and root-tip tissues were collected from 4 weeks-old plants (three replicates per genotype).
Our finding that 1.4% of the transcripts (>1 fpkm) began with, contained or ended in a Helitron was remarkably consistent with a study of full-length silkworm cDNA (123 of 8,654; 1.4%) collected from multiple tissues at different developmental stages (Han et al. 2013).
Lindner, J. R. et al. The Drosophila Perlecan gene trol regulates multiple signaling pathways in different developmental contexts.
