Owing to the underlying heterogeneity among included studies, such as differences in the tumor of origins (oral, pharynx, or larynx), multiple microarray platforms, different analytical approaches taken, and diverse endpoints, we sought to examine the validity of three staged classification of the HNSCC transcriptome.
Moreover, while any one locus can provide a misleading estimate of population structure, our use of multiple loci and different analytical methods allowed us to estimate species limits while taking into account the idiosyncrasies of each data set.
The RAPID framework was useful in supporting our analysis and exploring the multiple overlaps between the different analytical categories.
48 Different analytical techniques for the multiple case studies will be used, such as comparison of patterns, search for rival explanations and the construction of explications.
Several papers showed multiple risk estimates for the same exposure with different analytical approaches.
We employed multiple genetic loci, extensive taxon sampling, and several different analytical approaches to reconstruct the evolutionary history of the Sycophaginae.
We addressed this problem with different analytical strategies including complete cases only and multiple imputations including sensitivity analysis.
Similarly for metabolomics, different analytical samples can be obtained by applying multiple extraction protocols that target distinct metabolic compounds.
In this paper we employ multiple genetic loci, extensive taxon sampling over all known genera, and several different analytical approaches to discuss the generic delimitation and reconstruct the evolutionary history of sycophagine fig wasps.
Regarding drop-out and loss to follow-up, different analytical approaches (complete case analysis, last observation carried forward, multiple imputation, best/worst outcome) will be followed in order to assess their impact on the study results.
