Sentence examples for multiple developmental regulators from inspiring English sources

The key event of zygotic genome activation at MBT was extensive chromatin rearrangements followed by expression of multiple developmental regulators.

DOI: http://dx.doi.org/10.7554/eLife.09571.010 10.7554/eLiFigure71.011 Figure 2 figure supplement 3. EZH2 represses multiple developmental regulators in vivo.

Though genes such as fos and hsp70 have been known to be regulated by elongation, our results identify multiple critical developmental regulators such as smo (regulating Hedgehog signaling) [44], fst (regulating Transforming Growth Factor beta signaling) [45], and lfng (regulating Notch signaling) [46] as novel elongation targets of Spt5.

In multiple organisms, genes encoding developmental regulators are tightly controlled.

Developmental regulators of multiple lineages, such as Cdx4 and Runx1, which are associated with the bivalent marks H3K27me3 and H3K4me3 (Mikkelsen et al., 2007), similarly showed no gene ontology differences between those occupied by REST and those that were not.

Together, these results indicate that the TDIF ligand-PXY/TDR signal transduction pathway is an important regulator of multiple developmental processes [ 19].

Arabidopsis miRNAs [ 27] regulate multiple developmental events.

miRNAs regulate multiple developmental events in plants.

Albeit the current picture remains incomplete, the view emerges that multiple epigenetic mechanisms cooperate for repressing critical developmental regulators.

It is well known that expression of developmental regulators, including key transcription factors, is often regulated stochastically during cell differentiation, influencing cell and developmental decisions [ 70, 71].

Interestingly, Ubx target genes that contain multiple, distinct Ubx peaks tend to be enriched for genes encoding key developmental regulators (p<10−5 for both "DNA binding" and "imaginal disc development" in the haltere); Ubx target genes with only one peak are more enriched for regulators of metabolism and the cell cycle (not shown).