Sentence examples for multiple developmental genes from inspiring English sources

Consistent with this notion, Cobra1 depletion leads to elevated transcription of multiple developmental genes in ESCs without affecting the levels of Oct4, Nanog, or Sox2.

Microarray analysis showed up-regulation of multiple developmental genes such as Bmp8b, Grem1, Mmp12, Sema3c, Sema4c and Sema6c and transcription factors (TFs)- Gli2, Foxo1, Foxp2, Hoxb8, Pou2f1 and Zbtb32 at E17.5 in Pkd1 -/- mutant kidneys compared to WT.

In other studies BCL2 silencing induced cell death in vitro[ 43, 44], led to an arrest of cell cycle progression [ 19], and was associated with the downregulation of multiple developmental genes [ 45].

They encode transcription factors that control the expression of multiple developmental gene batteries.

The direct visual assessment of reporter gene expression enables the identification of functionally redundant genes, genes that operate in multiple developmental stages and genes whose functions in later development are obscured by an early lethal phenotype, all of them not easily amenable to classic genetic analysis.

Expression microarray analysis of multiple developmental stages grouped genes into five classes: maternally expressed, stably expressed, embryonic, embryo plus adult, and adult [ 28].

The search result is displayed by default as an overview table that summarizes the methylation profiles of genes across multiple developmental stages as well as gene information and chromosomal location.

Most notably, in developmental genes, multiple binding sites of different TFs are often located close to each other in genomes, forming so called cis-regulatory modules (CRMs), and work together to generate precise expression patterns [2].

Then we compared the genes detected in multiple developmental stages to determine whether there were root-period specific genes in addition to those unique to individual stage (Fig.  3e-f).

Sophisticated genetic engineering experiments in mice and the study of naturally occurring mutations in humans will continue to reveal the multiple developmental roles of T-box genes.

The gene ontology (GO) analysis of the 580 genes downregulated in Twin-DS-iPSCs revealed significant enrichment for genes involved in multiple developmental processes including embryonic development and morphogenesis, organ development and morphogenesis and system development.