Sentence examples for multiple depletion from inspiring English sources

To determine whether InteQuan can better control analytical variability during use of multiple depletion columns on clinical samples, 18 clinical samples in triplicate along with 12 aliquots of the HPS sample were analyzed in three experimental batches using three depletion columns in Study II.

These wavy structures with zonal (east west) wavelengths of about 150 880 km evolved later into either large-scale depletions or multiple depleted patches.

CD11c-DTR mice can support multiple DC depletions, up to six repeated injections of DT (4 ng/g) 3 days apart, without loss of weight and mortality observed in C57BL/6 transgenic mice (Zammit et al, 2005; and data not shown).

These include alteration of particle size distribution, strongly acidic soil reaction, organic matter depletion, multiple nutrient deficiencies (N, P, K and Zn) and low plant available water content.

It is not clear how the same mutation can be associated with either multiple deletions or depletion of mtDNA, but variability of clinical and molecular phenotypes seem to be common in PolG disease mutations [32].

However, in multiple myelomas DEPTOR depletion inhibited the proliferation of these cells and led to subsequent apoptotic events.

Recessive mutations in thymidine phosphorylase cause mitochondrial neurogastrointestinal encephalopathy, characterized by mtDNA depletion, multiple deletions and point mutations.

This dNTP imbalance interferes with mtDNA replication and results in depletion, multiple deletions, and point mutations, which in turn cause mitochondrial dysfunction.

The correlations of clinical, pathological, and molecular features in POLG encephalopathy are summarized in Table 4. Mutations in POLG cause a combination of mtDNA damage in the CNS including quantitative depletion, multiple deletions, and an increased burden of point mutations.

Autosomal recessive mutations in the thymidine kinase 2 gene (TK2) cause mitochondrial DNA depletion, multiple deletions, or both due to loss of TK2 enzyme activity and ensuing unbalanced deoxynucleotide triphosphate (dNTP) pools.

Specifically, while in EE, the accumulation of sulfide causes the inhibition of cytochrome c oxidase (COX), the systemic accumulation of thymidine and deoxyuridine in MNGIE determines an imbalance of the dNTP pool that interferes with mitochondrial DNA (mtDNA) replication and leads to depletion, multiple deletions and point mutations, and thus mitochondrial dysfunction.