Sentence examples for multiple deletions and from inspiring English sources
Notably, multiple deletions and the reciprocal duplications were identified at four separate loci.
We observed COCTs with multiple deletions and insertions of up to 18 bp in length.
Recessive mutations in thymidine phosphorylase cause mitochondrial neurogastrointestinal encephalopathy, characterized by mtDNA depletion, multiple deletions and point mutations.
Indeed, we found its ORF disrupted by multiple deletions and three premature stop codons (supplementary fig. S2, Supplementary Material online).
Reported sequence changes include point mutations, multiple deletions and microsatellite instability in coding and non-coding regions.
This dNTP imbalance interferes with mtDNA replication and results in depletion, multiple deletions, and point mutations, which in turn cause mitochondrial dysfunction.
Stowaway MITEs have undergone multiple deletions from and insertions into the same site in β-amylase intron 4 during the history of the tribe.
Combined, the phylogenetic distribution, sequence variation, and Entrez database comparisons indicate that a Stowaway-like element has undergone multiple deletions from and insertions into the same site in β-amylase intron 4 during the history of the tribe.
We are now using the Δp5236 parasites generated in this study as the basis for introducing additional marker-free gene deletions in order to generate a GAP-vaccine that is not only potent but also safe for human use, specifically GAPs that are compromised at multiple points of development (multiple-deletions) and without the addition of heterologous sequences (i.e. no resistance markers).
We examined whether the losses of insertion elements in genome interrupt the genome-wide transcriptional activity (i. e., the transcriptome) and whether these multiple deletions in genome and the heat shock stress exert common or different effects on transcriptional changes.
As shown in the case with multiple deletions of mtDNA and complex IV deficiency, the mitochondria devoid of COX-I immunoreactivity in Pattern III lesions are likely to lack complex IV activity.
