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However, these mice have multiple defects, ranging from abnormal spleen morphology to reduced numbers of CD4 and CD8 T cells as well as dendritic cells [29], [30].
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The category "DC defect" includes a range of defects ranging from cuticles of embryos that completed DC but do not hatch, to cuticles with large DC openings.
The penetrance of skeletal defects ranges from 42.8 to 61.1%.
The degree of these defects ranges from mild to severe.
Many of the 680 flawed ballots in the analysis of the overseas envelopes had multiple defects, so the total number of flaws exceeds the number of defective ballots.
As a result, the multiple defects can be assessed individually.
Patients with mixed defects, multiple defects, equivocal studies, and stress-only studies were excluded since well-defined defects were desirable in this first patient study.
Most notably, DNKv4 neurons display multiple defects during prolonged stimuli.
Wings with multiple defects were common, and similar defects were never observed in wild-type wings (Figure 2A).
However, dendritic defects are likely to be accompanied by multiple defects at the molecular level, in signaling pathways, metabolism, etc.
Previously reported Mib1−/− mice exhibited multiple defects in neurogenesis, somitogenesis, vasculogenesis, and cardiogenesis [13].
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