Sentence examples for multiple defects including from inspiring English sources

Palladin deficient mice die by day E15.5 and display multiple defects including defective cranial neural tube closure and fetal liver herniation indicating that palladin plays a critical role in embryonic development.

Mutations in MEC1 have been shown to lead to multiple defects, including sensitivity to DNA damage, impaired checkpoint functions, chromosome breakage, and loss of telomeric silencing [32], [33].

Mice lacking both genes have multiple defects, including duplicated neural tubes and malformed limb buds, whereas mice lacking either gene alone do not exhibit these defects [37], [38].

Igf1 knockout mice show multiple defects including reduced myelination and loss of striatal neurons [ 3].

Mice deficient in both Sulf1 and Sulf2 have multiple defects including skeletal and renal malformations, which result in neonatal lethality [ 186].

Mutant mice have smaller hearts with multiple defects including thinner ventricular walls, reduced myocyte proliferation and fewer intercalated discs (myocyte-specific junctional complexes responsible for electrical and force transduction).

Here, we show that the NK cells of aged mice have multiple maturation defects including reduced proliferation in vivo, multiple signs of immaturity, altered expression of activating and inhibitory receptors, and, intriguingly, altered expression of collagen-binding integrins.

Greatest decision of my life," said Sutton, 38, who was born with multiple health defects, including toes that were "bundled together".

Deficiency of both Akt1 and Akt2 resulted in multiple developmental defects including muscle atrophy [13].

Multiple organ defects, including in the kidneys and gonads, have been reported in Wt1 knockout mice [78].

Tim depletion caused multiple mitotic defects, including the loss of sister-chromatid cohesion, loss of mitotic spindle architecture, and a failure to exit mitosis.