The study used a within-subjects design with three conditions, corresponding to the number of available workspaces (see Figure 8): Figure 8 These pictures show people performing multiple collaborative data analyses in iPCA-CE.
Both replicate the key variation into multiple data sets, analyse each data set separately, and synthesize the replicated analyses into a final inference.
We applied blinding to treatment allocation for data collection, data entry, and analysis, and applied intention to treat analyses with multiple imputations in data analyses.
(13) Preserve the source code, multiple data sets, multiple analyses and parameter sets, the settings (for initial and boundary conditions, parameter scans, displays, solver choices, optimizers, Monte Carlo, etc)., the graphs of results, the investigator's notes and descriptions of procedures, plots, etc., all in a single, reproducible, exportable package.
It met with small to moderate resonance at first, but since 2008, Mackinnon [ 3] has observed a drastic increase in articles on applying multiple imputation to data analyses published in four leading medical journals (BMJ, JAMA, Lancet, NEJM).
Also and despite the fact that our assay has been validated in multiple cohorts and data analyses [ 10, 11, 14, 15, 17], neither survival advantage, nor improvement in quality of life has been demonstrated in a prospective randomized trial.
In order to cross-validate the results (triangulation), multiple data sources were analysed.
Mutations inside the CRISPR locus are also not included in the model, but in data analyses multiple spacers with sequence similarities can be subsumed into one identity.
A detailed statistical analysis plan (SAP) will be defined in advance to the final analysis, to fix detailed statistical considerations with regard to further data analyses, multiple test issue, missing value imputation and sensitivity analyses.
