Sentence examples for multiple daily dosing from inspiring English sources

As felodipine has poor and variable bioavailability, the multiple daily dosing is needed.

The multiple daily dosing not only has the issues with fluctuation of plasma drug concentration but may also lead to poor patients' adherence.

There may be effects of once-daily vs. multiple daily dosing with lithium on renal function (Carter et al. 2013; Castro et al. 2016).

The currently available systemic therapies provide about half of affected patients with meaningful pain relief and are further limited by unwanted adverse effects, such as drowsiness and dizziness, and the need for multiple daily dosing.

Thus, errors in dosing compliance by the patient or breakthrough pain in the case of pain medications commonly observed with multiple daily dosing (i.e. every 4 6 h) of an IR dosage form, can be easily mitigated by ingestion of a single tablet or capsule formulated as a CR, MR or ER product (henceforth abbreviated as 'MR dosage forms') (Smith et al. 2010).

A recent meta-analysis of eight studies reports that the average adherence for once-daily dosing was significantly higher than for multiple daily dosing (91.4% vs. 83.2%, respectively, P<0.001) [35].

Multiple daily doses were even more effective than the same total amount of RTL given as a single dose.

Because nausea may correlate with lithium levels, especially peak levels, taking lithium after meals, using a multiple daily dose regimen or using sustained release preparations may diminish nausea.

The six volunteers that were hospitalized all received multiple daily doses, the first one of which was given on 7 January.

These data suggest the possibility of administering a single dose of DepoFoam-encapsulated ProGP to improve hematopoietic recovery time after chemotherapy, and for other indications that require multiple daily doses of ProGP.

Oxybutynin is the current gold standard drug for management of overactive bladder (OAB) in children, but can have significant side effects or be difficult to administer in multiple daily doses.