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Multiple daily doses were even more effective than the same total amount of RTL given as a single dose.
Oxybutynin is the current gold standard drug for management of overactive bladder (OAB) in children, but can have significant side effects or be difficult to administer in multiple daily doses.
These data suggest the possibility of administering a single dose of DepoFoam-encapsulated ProGP to improve hematopoietic recovery time after chemotherapy, and for other indications that require multiple daily doses of ProGP.
The six volunteers that were hospitalized all received multiple daily doses, the first one of which was given on 7 January.
These compounds are intended to optimize and maintain ADHD symptom control throughout the day, while eliminating problems associated with short-acting medications, such as the need for in-school, midday or multiple daily doses.
Multiple daily doses of aminoglycosides are discouraged, because this regimen does not reduce toxicity and cannot provide sufficient peak serum concentrations; peak concentration should be determined 30 minutes after the end of the infusion and trough concentration just before the next infusion.
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The currently available systemic therapies provide about half of affected patients with meaningful pain relief and are further limited by unwanted adverse effects, such as drowsiness and dizziness, and the need for multiple daily dosing.
As felodipine has poor and variable bioavailability, the multiple daily dosing is needed.
There may be effects of once-daily vs. multiple daily dosing with lithium on renal function (Carter et al. 2013; Castro et al. 2016).
Because nausea may correlate with lithium levels, especially peak levels, taking lithium after meals, using a multiple daily dose regimen or using sustained release preparations may diminish nausea.
The multiple daily dosing not only has the issues with fluctuation of plasma drug concentration but may also lead to poor patients' adherence.
More suggestions(15)
multiple daily trips
multiple daily walks
multiple daily attacks
multiple daily decisions
multiple daily departures
multiple daily newspapers
multiple daily airings
multiple daily phlebotomies
multiple daily ingestions
multiple daily reminders
multiple daily meetings
multiple fractionated doses
multiple daily tours
multiple daily applications
multiple daily showers
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