Sentence examples for multiple cytokines has from inspiring English sources

Production of multiple cytokines has been associated with protection from disease progression in HIV [4] but not TB [6].

Functionality of T-cell responses in terms of quality or capacity to secrete multiple cytokines has been shown critical in relation to the protection capacity of the T-cell response [27].

Production of multiple cytokines has been associated with protection from disease progression 10.

148, 149 Tofacitinib, a JAK inhibitor that blocks signaling of multiple cytokines, has shown promising results and is approved for the treatment of RA. 150 A long-term open-label study of tofacitinib is currently enrolling JIA patients to assess safety and tolerability of this medicine in the pediatric population.

Multiple cytokines have been linked to disease in MRL/ lpr mice, including IFNγ (Haas et al., 1997; Santoro et al., 1983), IL-6 (Cash et al., 2010; Tang et al., 1991), IL-1β (Boswell et al., 1988; Lemay et al., 1996) and IL-18 (Esfandiari et al., 2001; Favilli et al., 2009).

SOCS3 is induced by multiple cytokines and has been suggested to be inhibitory for both IL-6 and IL-10 in vitro.

Adipose tissue as an endocrine organ is responsible for the release of multiple cytokines, which have the most diverse metabolic functions.

Overproduction of cytokines has been implicated in chronic fatigue syndrome.

Low affinity of IL-10Rβ for cytokines has impeded efforts aimed at crystallizing cytokine-receptor complexes.

Brain cytokines have multiple important roles in the developing nervous system (Deverman and Patterson 2009), such that any alteration in their levels during the early postnatal period would have deleterious effects on the CNS.

Thus, although type I IFNs have been extensively studied for over three decades and multiple facets of these cytokines have been described including their role in the inhibition of viral replication, the activation of cytotoxic NK- and T-cell responses, the regulation of T-helper-cell function and the modulation of DC function (Gough et al, 2012), there is still more to be learnt.