Sentence examples for multiple crystal structures from inspiring English sources

Multiple crystal structures elucidate the structural basis of multi-ligand gating in GsuK, and also reveal a unique ion conduction pore with segmented inner helices.

And by determining multiple crystal structures, Kong et al. were able to understand, from a structural point of view, how these ligands regulate this channel, and to propose a gating mechanism that is distinct from the mechanisms that are known to control other potassium channels.

Herein, we applied docking-based virtual screening (VS) using the multiple crystal structures to identify several potent CDK8 inhibitors.

We have solved multiple crystal structures of the major capsid proteins VP16 and VP17 of bacteriophage P23-77.

The appropriate use of multiple crystal structures obtained a better enrichment of CDK8 conformations to cope with the protein flexibility.

In the cases when multiple crystal structures of the same sequence similarity to the target proteins are available, how to select the most relevant structures as templates for homology modeling becomes critical.

These three residues are highly conserved across species and interact with structurally diverse PXR agonists, as evidenced by multiple PXR crystal structures.

As an additional data set, we assembled a diverse set of well-known drug targets that have multiple crystal complex structures available, and generally display significant sidechain movement upon binding to different ligands [35] (Table 2).

Multiple solvent crystal structures (MSCS) of porcine pancreatic elastase were used to map the binding surface the enzyme.

Catalysis in organic solvents and the mapping of protein surfaces using multiple solvent crystal structures are two rapidly developing areas of research.

Here, we use a combination of multiple solvent crystal structures and computational solvent mapping (FTMap) to determine binding site hot spots in the "off" and "on" allosteric states of the GTP-bound form of H-Ras.