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Typical professional development activities included teaching multiple courses during the graduate program, videotaping for self-evaluation, written training manuals, weekly meetings prior to teaching, and semester-long courses (Rushin et al., 1997), activities similar to those suggested by graduate students to improve their professional development as teachers (Nyquist et al., 1999).
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We report a longitudinal study of the gut microbiome based on DNA sequence analysis of monthly stool samples and clinical information from 39 children, about half of whom received multiple courses of antibiotics during the first 3 years of life.
Multiple courses of aminoglycosides during the neonatal period would thus inhibit the clearance process.
If patients had multiple courses of MV during their hospitalization, only the first episode was evaluated.
However, patients with myeloma typically receive multiple courses of treatment during the course of the disease, the sequencing of which may or may not be important.
There is also some evidence that repeated treatment with growth factors during multiple courses of chemotherapy may deplete the stem cell compartment and give rise to genomic alterations, even though these issues remain controversial [33], [34].
Lung cancer is considered usually to acquire resistance to chemotherapy during multiple courses of therapy, which leads to poor prognosis, compared with other types of human malignancies.
For patients with multiple courses of therapy with fluconazole during the same admission, only those who had neutropenia and fever prior to the first course of fluconazole therapy were included in the final study cohort.
Each individual patient received multiple courses of chemotherapy and was followed several times during each course of therapy.
For patients with multiple courses of chemotherapy (based on a gap of ≥60 days between the last administration of chemotherapy in a given course and the first administration in the next course) during the study period, all courses were considered.
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Justyna Jupowicz-Kozak
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