Sentence examples for multiple copy amplification from inspiring English sources
The second region of segmental loss at 17q21.1-q21.31 is followed by a large segmental gain and a second discrete multiple copy amplification at 17q25.1.
Karyotypic analysis of murine metaphases from all the host-derived tumours showed mostly pseudodiploid chromosome constitutions, with multiple copies (amplification) of mouse chromosome 15 and the absence of a typical Y chromosome.
We tested the effect of GANT-61 on two other NB cell lines, NBL-W-S and SK-N-BE(2), which have multiple-copy MYCN amplification.
Such an intensive interactive environment may increase the chance of aberrant DNA amplification, and thus form multiple copy number inverted repeats or tandem repeat regions on these chromosomes.
IS6110 was chosen because of multiple copy numbers of IS6110 (6 to 24) in the MTB genome, making it an attractive target for PCR amplification [5].
The net result is synthesis of multiple copies of cDNA in a single amplification step.
Because PCR amplification can produce multiple copies of the same integration site, only tags with unique paired end alignments were used for further analysis.
The log2 ratios for these amplifications (particularly for MY2) indicated a roughly four-fold amplification, suggesting the presence of multiple copies of the retrotransposon.
The extra lac copies provided by multiple copies of a plasmid with an internal lac amplification are sufficient to allow immediate exponential growth under selection and development of an unstable revertant colony with an expanded tandem lac amplification.
In dinoflagellates, however, the genome has undergone further substantial modifications, including massive genome amplification and recombination resulting in multiple copies of each gene and gene fragments linked in numerous combinations.
After selection on agar plates containing YPD supplemented with 100 μg/mL zeocin, the transformants were subjected to a general procedure for the selection of clones containing multiple copies of the expression cassette, called Posttransformational Vector Amplification (PTVA) process [ 13].
