Reactive oxygen species can attack multiple cellular constituents including protein, nucleic acids, and lipids, leading to disruption of cellular function and integrity [ 56, 57].
In fact, the entire path of the mRNA in the 40S subunit is visible, identifying multiple interactions with initiation factors or ribosome constituents, including contacts of eIF2α-D1 and uS7 (using the nomenclature of Ban et al., 2014), with the −3 position of mRNA previously identified as important.
ROS include less-reactive ROS and high ROS (hROS); high levels of both less-reactive ROS and hROS can oxidize cell constituents, including DNA, proteins and lipids and active multiple apoptosis pathways including mitogen-activated protein kinase, Fas-FasL, NF- κB, DNA damage response (DDR) and p53 signaling pathways.
The catalyst layer (CL) of the polymer electrolyte membrane (PEM) fuel cell is comprised of multiple constituent materials including platinum catalyst, carbon support and ionomer.
These changes of functional connectivity, ALFF, and ReHo in resting state suggest how alcohol affected the DMN which is responsible for multiple constituent functions, including action, cognition, emotion, interoception, and perception [ 26, 27].
Cruciferous vegetables and their biologically active constituents, including isothiocyanates (ITCs) such as sulforaphane (SFN), appear to modulate prostate cancer risk at multiple stages of carcinogenesis.
The growing body of experimental, preclinical, and clinical evidence supporting GSPE exerting beneficial biological activities in multiple medical conditions, has led to increased interest in its bioavailability, metabolism, and distribution of the primary GSPE phenolic constituents, including gallic acid, epicatechin, proanthocyanidin dimers, and larger oligomers.
And he said his constituents, including many Republicans, had taken notice of events in Washington.
And he is legendary for his service to constituents, including the Catholics in his district.
Plasma exchange (PEX) removes circulating plasma constituents including immunoglobulins.
