Sentence examples for multiple conformations that from inspiring English sources

Thus, we would expect that using multiple conformations that represent most of the conformational diversity of a protein could improve the sensibility of our approach.

Firstly, these biopolymers can occur in multiple conformations that can have distinct functionality, with the predominant conformer depending on the molecule's environment, for instance, the presence of a particular binding partner (12 16).

These data show that PGG/GGG exists in multiple conformations that are not fully competent for ligand binding or catalysis.

To address this problem, we have developed a computationally efficient ActiveGEnSeMBLE method that systematically predicts multiple conformations that are likely in the GPCR activation landscape, including multiple active- and inactive-state conformations.

Thus, for proteins with multiple conformations that are close in energy, such as many intrinsically disordered proteins, residues distant from the active site can alter both binding affinity and specificity.

As a result, we simulated a dataset of a molecular complex with multiple conformations that are fixed in ice with random orientations.

Hence, oligo J4/5 folds into multiple junction conformations that interconvert between each other (summarized in Figure 2D).

These EPR measurements indicate that the ligand binding loops of these TBDTs exist in multiple conformations and that these conformations are in equilibrium.

Each of these may include multiple 3-D conformations that are sampled to remove redundancy, guaranteeing a minimum (non-hydrogen atom pair-wise) root-mean-square distance (RMSD) between conformers.

Qin and colleagues [ 2]provide data that clearly illustrate that the binding sites have multiple pre-existing conformations that can select the partner.

We resolve multiple pre-hydrolysis conformations that can be ordered into a sequence to trace out smooth trajectories of domain movements for GroEL-ATP7 and GroEL-ATP14 complexes.