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It was introduced for microarray data which contains thousands of genes together with multiple conditions by Fellenberg et al.[ 37].
Statistical analysis was performed to assess the difference between 2 groups under multiple conditions by one-way analysis of variance, followed by Bonferroni multiple comparison tests.
We subsequently confirmed the advantage of OR over chi-squared and G test statistic in multiple conditions, by varying N, M, and the influence of aneuploidy (U) (table 1).
EBSeq simultaneously assesses DE between multiple conditions by assigning a posterior probability to each possible expression pattern in an enumerated list of all possible expression patterns, given a set of conditions.
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41 Paper based single disease guidelines are intrinsically limited by being hard to integrate for people with multiple conditions and by being unable, for reasons of length and usability, to document all possible interactions.
The difference between two groups under multiple conditions was assessed by one-way analysis of variance (ANOVA) followed by Boneferroni's multiple comparison tests using PRISM statistical analysis software (GraphPad Software, San Diego, CA, USA).
Further research could explore this issue by linking the different data sources to explore whether multiple conditions are underreported, or by following individuals over an extended time period and examine the number of different diagnoses given to the same individual.
The approach was successfully extended by Roy et al. to learn dynamic networks across multiple conditions [ 15], and by Gill et al. to assess the overall evidence of network differences between two conditions using the connectivity scores associated with a gene or module [ 16].
Myocardial damage can be caused by multiple conditions including ischemia, trauma, toxins or inflammation.
Children affected by multiple conditions were counted in each group for condition-specific analyses but were counted only once in the overall analyses.
Alternatively, the traits that are being selected upon by multiple conditions could be negatively correlated (as above), constraining their response (Arnold 1992; Etterson and Shaw 2001; Fig. 1C).
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