Sentence examples for multiple concomitant medications from inspiring English sources

Furthermore, elderly patients are typically underrepresented in clinical trials, and the patients of advanced age who are included in clinical trials are often less frail compared with typical geriatric patients who present with comorbidity and multiple concomitant medications.

The dramatic increase in prescriptions also raises concerns for patient safety and the potential for iatrogenic harm, particularly as many older adults now take multiple concomitant medications [ 14- 16].

Older individuals use more medications than any other age group. 1 They typically suffer from multiple acute and chronic diseases, which often necessitates the use of multiple concomitant medications.

This randomized, prospective, controlled trial revealed that linagliptin was efficacious and well tolerated in older patients with T2DM who had a high burden of comorbid conditions and who were on multiple concomitant medications.

Saxagliptin used in initial combination therapy with metformin was also superior to metformin monotherapy in antidiabetic drug-naïve older patients, many of whom were taking multiple concomitant medications, and the improvement in glycemic measures with saxagliptin was numerically greater in the older group than in the younger group.

With little difference among the PPIs in terms of clinical efficacy at equivalent doses, differences in drug interaction propensities become important factors in prescribing decisions, particularly in patients who are taking multiple concomitant medications (such as the elderly) or those receiving drugs with a narrow therapeutic window.

Persons with Ad are a particularly vulnerable group, and thus it is important to assess whether the risk benefit profile, estimated in trials that have often excluded aged individuals, those with cognitive impairment, multiple comorbidities or concomitant medications, is directly applicable.

Many patients with venous thromboembolism (VTE) are elderly, have multiple comorbidities and take several concomitant medications.

Few differences were observed between the treatment cohorts; the use of multiple mood stabilizers and other concomitant medications made it difficult to attribute reported outcomes to any one treatment group, and thus elucidate the role of individual medications.

All these factors make this an ideal drug for use in the elderly and it appears that the risk of adverse events is minimal even in those with multiple medical problems and concomitant medication use.

In general, they had multiple comorbidities with approximately two-thirds of patients taking five or more concomitant medications in addition to their diabetes treatment.