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To date, multiple compounds have been tested in pre-clinical studies and phase ll clinical trials.
Multiple compounds have been identified that sensitize cancer cells to TRAIL-induced apoptosis.
In fact, therapies based on coordinated actions of multiple compounds have been used as early as the dawn of medicine.
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He also prescribes a topical solution that includes Rogaine and Propecia to be applied twice daily: "I found the interaction of multiple compounds has a synergetic effect".
Transfer of resistance to multiple compounds has been shown to occur through plasmid exchange in natural environments, even between phylogenetically diverse populations.
Multiple N-nitroso compounds have been observed in animal studies to be both mutagenic and teratogenic.
Multiple N-nitroso compounds have been observed in animal studies to be both mutagenic and teratogenic in nature [ 2- 11].
To address the issue that many compounds have multiple targets, we chose multiple sets with varying overlap in their targets with the targets of our PaCa inhibitors.
Low IC50 inhibition by structurally diverse BFRs, including parent compounds and metabolites, suggests that low-dose exposure to multiple compounds could have an additive effect, reducing the concentration required of a single compound for endocrine disruption.
The Food Quality Protection Act (1996) requires the U.S. Environmental Protection Agency to evaluate both children's aggregate exposure (multiple exposure pathways for a single pesticide) and cumulative risk (potential health effects from exposure to multiple compounds that have a common mechanism of toxicity).
Nitroaromatic compounds have multiple applications in the chemical industry, amongst which special attention should be paid to 2,4,6-trinitrotoluene (TNT) due to its extensive use throughout the world (Harter 1985).
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