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These results showed that face adaptation involves multiple complex effects.
Given these multiple, complex effects, it is likely that p53 activity is under extremely tight control and that several, overlapping mechanisms may concur to set tissue- and cell-specific thresholds for p53 activation in response to different types of stimuli.
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Given multiple and complex effects of this hormone, interaction between the lice induced responses and stress is of considerable interest.
Recent research has demonstrated that maternal undernutrition has multiple and complex effects on the homeostatic and pathophysiological mechanisms in neonates and older offspring [ 16- 18].
Disturbance histories drive spatiotemporal patterns of species distributions, and multiple disturbances can have complex effects on these patterns of distribution.
Recent studies have shown that proximal arrangement of multiple genes can have complex effects on gene expression.
The technique leaves no other DNA in the genome, such as marker genes, and can be used serially to effect multiple complex changes in any desired chromosomal locations.
Likewise, the advance might help identify new pathogens in honeybees and unravel the complex effects of multiple combinations of pathogens and environmental toxins.
But because exercise triggers complex effects in multiple tissues and organs, "it's no surprise that other factors could be found here," says metabolic physiologist Christopher Newgard of Duke University Medical Center in Durham, North Carolina, who wasn't connected to either the irisin or BAIBA research.
Pb has broad and complex effects on multiple intracellular signaling pathways.
Results so far suggest that, although some dosage-sensitive genes might have strong effects on their own, it is likely that many of the phenotypes associated with DS are due to complex effects of multiple Hsa21 genes.
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