Sentence examples for multiple complex changes from inspiring English sources

The technique leaves no other DNA in the genome, such as marker genes, and can be used serially to effect multiple complex changes in any desired chromosomal locations.

Chronic alcohol consumption results in multiple complex changes in the lung.

In contrast, two neoplasms with serous papillary and mixed mullerian morphological features shared multiple complex changes as well as cytogenetic evidence of intratumoral heterogeneity.

This may account for the occurrence of multiple and complex changes in neuronal and glial functions even before manifest vascular anomalies in diseases such as diabetic retinopathy can be detected [21] [23], and suggests that the vascular pathology may be a consequence of disturbed glial cell functions.

It may be, therefore, that the tub chromosome contains multiple or complex changes that cannot be as easily dissected by site-specific recombination mapping.

Strong associations between NAFLD and multiple complex metabolic and proinflammatory changes that have an effect on the vasculature [ 15] indicate that it is very difficult to identify causality from the relationship between NAFLD, PWV and CVD.

The strong associations between NAFLD and multiple complex metabolic and proinflammatory changes that have an effect on the vasculature (13, 14) mean that it is very difficult to identify causality in assessing the relationship between NAFLD, IR, and CVD.

Network science and systems biology-based approaches, using machine learning and network science principles, that integrate multiple data sources, can uncover complex changes in a biological system.

The genesis and progression of melanoma arise from complex changes in multiple signaling pathways that control cell proliferation and the ability to evade cell death processes.

Instead, these data show frequent, cyclic adaptations to the weather, infrequent fundamental change over time, and when change does occur, it is for multiple complex reasons.

Effecting change in clinical practice involves multiple, complex, dynamic, professional and social adjustments affecting different layers of an organization [ 43, 44].