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The first p-value will remain significant after a Bonferroni-like correction for the multiple comparisons, but the second will not.
Planned post-hoc t-test comparisons revealed that the control group exhibited significantly greater levels of responding in the first ten minutes of reinstatement testing than the 2.5 µg CART group (p<.05, adjusted for multiple comparisons), but not the TTX- or 0.625 µg CART- treated groups.
Before scanning, the twelve participants included in the fMRI experiment rated (Figure S1) the 6 disgust scripts as more disgusting than the neutral ones (two-tailed matched pair t-test, p<0.001 uncorrected for multiple comparisons) but their was no significant difference between the disgusting and neutral scripts in terms of how pleasant (p>0.07) or how hard they were to imagine (p>0.87).
This approach avoids multiple comparisons, but it exploits all available information without reductions to scales.
Fifth, we did not adjust for multiple comparisons, but we report all associations that we tested.
No correction was made for multiple comparisons, but as recommended in these circumstances, relevant analyses are shown in full.
Similar(30)
The least squares mean difference (95% confidence interval) in HAMA total score change from baseline (MMRM) was statistically significant for vilazodone 40 mg/day versus placebo (–1.80 [–3.26, –0.34]; P =.0312 [adjusted for multiple comparisons]), but not for vilazodone 20 mg/day versus placebo.
Genotype differences were present in stance width (two-way ANOVA main effect of genotype F1,62 = 16.51, p < 0.0001; limb F1,62 = 70.90, p < 0.0001; Interaction F1,62 = 0.381, p = 0.539, Sidak's multiple comparisons test), but no other abnormalities were observed.
Post-trial, there was a significant decrease in the median perceived difficulty of leukaemia in the Study group (median rating pre-trial 9; post-trial 6, P < 0.001, Dunn's multiple comparisons test), but not in the Control group (median rating pre-trial 8; post-trial 7).
No formal correction for multiple comparisons was made, but efforts were made to reduce the number of outcomes where appropriate.
No corrections for multiple comparisons were made, but by reporting the exact p values this can easily be performed with a preferred method.
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