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The significance level for the univariable model was 0.05 (95%% confidence interval), while the significance level for the multivariable model was 0.01 (99%% confidence interval) as to minimize type I error that may result from multiple comparison in the multivariable log binomial regression model.
The BWSTT group had significantly greater improvement than the PT group (Mann-Whitney U test, Bonferroni adjustment for multiple comparison) in ambulation speed at 1 month (BWSTT=8.5; PT=10.8; P<.005); and in the number of steps at 1 (BWSTT=20.0; PT=22.7; P<.005), 2 (BWSTT=19.5; PT=22.4; P<.005), 3 (BWSTT=20.1; PT=23.1; P<.005), and 4 months (BWSTT=21.0; PT=23.0; P=.006).
Multiple comparison in the proliferation studies was handled with ANOVA followed by Dunnett's post-test.
We calculated a nonparametric randomization test that controls for multiple comparison in order to identify spatial-spectral clusters of differences between the tinnitus and the control group.
> -wrap-foot> Negative correlations were observed in two significant clusters (P < 0.005, corrected for multiple comparison), in the right posterior cerebellum and right temporal lobe (BA 22, 39, 40).
The added power of this two-stage procedure derives from the fact that the multiple comparison in the second step is performed only based on the genes chosen in the first step, not the entire set of genes.
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We performed multiple comparisons in analyzing our data without adjustment, increasing the likelihood of false-positive associations.
Finally, it should be noted that Geomfinder is not intended for simultaneous multiple comparisons in a large number or families of proteins.
The voxel-wise comparison of the amplitude of resting activity showed higher amplitudes (p < 0.05, corrected for multiple comparisons) in the left parietal lobe in all frequency ranges in MWA compared to MWoA.
We did not consider adjustment for multiple comparisons in this exploratory, hypothesis-generating set of analyses.
Moreover, the use of correction for multiple comparisons in this area is debated [45].
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